Lake Titicaca, located on the border between Bolivia and Peru, was named after just what you think it was. The toponym was bestowed in 1955 after a troupe of burlesque performers ate some questionable seafood while working in the area. The lake was formerly known as Lake Poopyboobies after a similar mishap in 1928.

Source : Mack, Beth. Place Names and Their Origins, 1968.